Pocket proteins and cell cycle control
نویسندگان
چکیده
منابع مشابه
Pocket proteins and cell cycle regulation in inner ear development.
Loss of neurosensory cells of the ear, caused by genetic and non-genetic factors, is becoming an increasing problem as people age, resulting in deafness and vestibular disorders. Unveiling useful mechanisms of cell cycle regulation may offer the possibility to generate new cells out of remaining ones, thus providing the cellular basis to induce new hair cell differentiation in the mammalian ear...
متن کاملCataloging proteins in cell cycle control.
Bioinformatics makes a number of methods available that can also be used to identify cell cycle related proteins. Nevertheless, few tools are specifically designed to cope with cell cycle proteins. In fact, a vast amount of data is currently scattered among many databases. Here, we present a first detailed analysis of known cell cycle proteins. We combined databases mining and literature search...
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During the development of multicellular organisms, many different cell types are created. These display characteristic cell cycle programs that can radically change during the organism’s lifetime (Jakoby and Schnittger, 2004; Fig. 1). Usually, in younger and less differentiated tissues, a proliferative cell cycle mode occurs. In this mitotic cell cycle program, DNA replication (also known as th...
متن کاملPocket proteins critically regulate cell cycle exit of the trabecular myocardium and the ventricular conduction system
During development, the ventricular conduction system (VCS) arises from the trabecular or spongy myocardium. VCS and trabecular myocytes proliferate at a significantly slower rate than compact zone myocardial cells, establishing a transmural cell cycle gradient. The molecular determinants of VCS/trabecular myocyte cell cycle arrest are not known. Given the importance of pocket proteins (Rb, p10...
متن کاملSwitching the cell cycle. Kip-related proteins in plant cell cycle control.
During the development of multicellular organisms, many different cell types are created. These display characteristic cell cycle programs that can radically change during the organism’s lifetime (Jakoby and Schnittger, 2004; Fig. 1). Usually, in younger and less differentiated tissues, a proliferative cell cycle mode occurs. In this mitotic cell cycle program, DNA replication (also known as th...
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ژورنال
عنوان ژورنال: Oncogene
سال: 2005
ISSN: 0950-9232,1476-5594
DOI: 10.1038/sj.onc.1208619